rs13429458

plus

Geno	Mag	Summary
(A;A)	0	common in complete genomics
(A;C)		0.67x Lower risk of PCOS for Han Chinese
(C;C)		0.67x Lower risk of PCOS for Han Chinese

Reference

GRCh38 38.1/141

Chromosome

2

Position

43411699

Gene

THADA

is a	snp
is	mentioned by
dbSNP	rs13429458
dbSNP (classic)	rs13429458
ClinGen	rs13429458
ebi	rs13429458
HLI	rs13429458
Exac	rs13429458
Gnomad	rs13429458
Varsome	rs13429458
LitVar	rs13429458
Map	rs13429458
PheGenI	rs13429458
Biobank	rs13429458
1000 genomes	rs13429458
hgdp	rs13429458
ensembl	rs13429458
geneview	rs13429458
scholar	rs13429458
google	rs13429458
pharmgkb	rs13429458
gwascentral	rs13429458
openSNP	rs13429458
23andMe	rs13429458
SNPshot	rs13429458
SNPdbe	rs13429458
MSV3d	rs13429458
GWAS Ctlg	rs13429458

GMAF

0.1713

Max Magnitude

0

?

(A;A) (A;C) (C;C)

28

GWAS snp
PMID	[PMID 21151128]
Trait
Title	Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33
Risk Allele	A
P-val	2E-23
Odds Ratio	1.4900 [1.39-1.61]

[PMID 22009367] Susceptibility Loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21, and 9q33.3 in a cohort of caucasian women

[PMID 22081247] Family-based analysis of susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3

[PMID 22504079] Association of polycystic ovary syndrome susceptibility single nucleotide polymorphism rs2479106 and PCOS in Caucasian patients with PCOS or hirsutism as referral diagnosis.

[PMID 22547425 ] Variants in DENND1A Are Associated with Polycystic Ovary Syndrome in Women of European Ancestry.

[PMID 23208300] Genotype-phenotype correlations of PCOS susceptibility SNPs identified by GWAS in a large cohort of Han Chinese women

[PMID 22902918] Variants in DENND1A and LHCGR are associated with endometrioid adenocarcinoma

GWAS snp
PMID	[PMID 22952603 ]
Trait	Response to amphetamines
Title	Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).
Risk Allele
P-val	6E-6
Odds Ratio	NR NR

GWAS snp
PMID	[PMID 22885925]
Trait	Polycystic ovary syndrome
Title	Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome.
Risk Allele	A
P-val	4E-13
Odds Ratio	1.49 [NR]

[PMID 29727258] Association study between variants in LHCGR DENND1A and THADA with preeclampsia risk in Han Chinese populations.