| Geno
|
Mag
|
Summary
|
| (C;C)
|
0
|
common in complete genomics
|
| GWAS snp
|
| PMID
|
[PMID 19654303 ]
|
| Trait
|
Lung cancer
|
| Title
|
Deciphering the Impact of Common Genetic Variation on Lung Cancer Risk: A Genome-Wide Association Study
|
| Risk Allele
|
|
| P-val
|
0.000003
|
| Odds Ratio
|
1.26 [NR]
|
[PMID 21303977] Genome-wide significant association between a sequence variant at 15q15.2 and lung cancer risk.
In this study, we sought to confirm 7 variants with suggestive association to lung cancer (P < 10(-5)) in a recently published meta-analysis. In a GWA dataset of 1,447 lung cancer cases and 36,256 controls in Iceland, 3 correlated variants on 15q15.2 (rs504417, rs11853991, and rs748404) showed a significant association with lung cancer, whereas rs4254535 on 2p14, rs1530057 on 3p24.1, rs6438347 on 3q13.31, and rs1926203 on 10q23.31 did not.
]
