rs4254535

plus

Geno	Mag	Summary
(T;T)	0	common in complete genomics

Make rs4254535(C;C)

Make rs4254535(C;T)

Reference

GRCh38 38.1/141

Chromosome

2

Position

68971256

is a	snp
is	mentioned by
dbSNP	rs4254535
dbSNP (classic)	rs4254535
ClinGen	rs4254535
ebi	rs4254535
HLI	rs4254535
Exac	rs4254535
Gnomad	rs4254535
Varsome	rs4254535
LitVar	rs4254535
Map	rs4254535
PheGenI	rs4254535
Biobank	rs4254535
1000 genomes	rs4254535
hgdp	rs4254535
ensembl	rs4254535
geneview	rs4254535
scholar	rs4254535
google	rs4254535
pharmgkb	rs4254535
gwascentral	rs4254535
openSNP	rs4254535
23andMe	rs4254535
SNPshot	rs4254535
SNPdbe	rs4254535
MSV3d	rs4254535
GWAS Ctlg	rs4254535

GMAF

0.2952

Max Magnitude

0

?

(C;C) (C;T) (T;T)

28

GWAS snp
PMID	[PMID 19654303 ]
Trait	Lung cancer
Title	Deciphering the Impact of Common Genetic Variation on Lung Cancer Risk: A Genome-Wide Association Study
Risk Allele
P-val	0.000005
Odds Ratio	1.12 [NR]

[PMID 21303977 ] Genome-wide significant association between a sequence variant at 15q15.2 and lung cancer risk.

In this study, we sought to confirm 7 variants with suggestive association to lung cancer (P < 10(-5)) in a recently published meta-analysis. In a GWA dataset of 1,447 lung cancer cases and 36,256 controls in Iceland, 3 correlated variants on 15q15.2 (rs504417, rs11853991, and rs748404) showed a significant association with lung cancer, whereas rs4254535 on 2p14, rs1530057 on 3p24.1, rs6438347 on 3q13.31, and rs1926203 on 10q23.31 did not.