|heroin addiction in hispanics|
||Hispanics may be at increased risk of heroin addiction.
commonly referred to as A779C
Only for Hispanics, individuals who have a genoset composed of rs1799913(C;C) and rs7963720(T;T) are reported to be at 14x higher risk for developing heroin addiction (CI:0.83-244.63, p=0.012).[PMID 18181017]
Again, only for Hispanics, individuals having a genoset composed of rs1799913(C;C) and rs4290270(T;T) are reported to be at 9x higher risk for developing heroin addiction (CI:0.5-153, p=0.063).[PMID 18181017]
[PMID 17521439] Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach.
[PMID 20580984] Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers.