rs1864010
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | reduced colorectal risk | |
| (A;G) | reduced colorectal risk | |
| (G;G) | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 19 |
| Position | 7294494 |
| Gene | INSR |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1864010 |
| dbSNP (classic) | rs1864010 |
| ClinGen | rs1864010 |
| ebi | rs1864010 |
| HLI | rs1864010 |
| Exac | rs1864010 |
| Gnomad | rs1864010 |
| Varsome | rs1864010 |
| LitVar | rs1864010 |
| Map | rs1864010 |
| PheGenI | rs1864010 |
| Biobank | rs1864010 |
| 1000 genomes | rs1864010 |
| hgdp | rs1864010 |
| ensembl | rs1864010 |
| geneview | rs1864010 |
| scholar | rs1864010 |
| rs1864010 | |
| pharmgkb | rs1864010 |
| gwascentral | rs1864010 |
| openSNP | rs1864010 |
| 23andMe | rs1864010 |
| SNPshot | rs1864010 |
| SNPdbe | rs1864010 |
| MSV3d | rs1864010 |
| GWAS Ctlg | rs1864010 |
| GMAF | 0.4275 |
| Max Magnitude | 0 |
[PMID 17914103] The INSR A-603G promoter rs1864010 SNP, which is located within a known Sp1-binding site, was associated with the risk of colorectal cancer, with carriers of the G allele having a decreased risk (odds ratios 0.71, CI: 0.54-0.93). Carrying the variant allele of the IRS1 Gly972Arg rs1801278 SNP further decreased the risk among the INSR-603G allele carriers (OR 0.28, 95% CI 0.11-0.70).
[PMID 16209714
] The distribution of SNPs in human gene regulatory regions.
