rs2075650(G;G)
From SNPedia
| possibly 4x higher Alzheimer's risk |
| Is a | genotype |
| of | rs2075650 |
| Gene | TOMM40 |
| Chromosome | 19 |
| Position | 44,892,362 |
| mentioned | by |
| Magnitude | 2 |
| Repute | Bad |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | normal; some association with greater longevity |
| (A;G) | 2 | possibly 2x higher Alzheimer's risk |
| (G;G) | 2 | possibly 4x higher Alzheimer's risk |
Recent work suggests, however, that the linkage disequilibrium between rs2075650 and the ApoE ε4 defining SNP rs429358 means that there may be little, if any, independent effect of rs2075650 on Alzheimer's risk.
