rs2238135
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | normal risk | |
| (C;G) | ? | |
| (G;G) | 2.47x higher risk for prostate cancer |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 47884407 |
| Gene | VDR |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2238135 |
| dbSNP (classic) | rs2238135 |
| ClinGen | rs2238135 |
| ebi | rs2238135 |
| HLI | rs2238135 |
| Exac | rs2238135 |
| Gnomad | rs2238135 |
| Varsome | rs2238135 |
| LitVar | rs2238135 |
| Map | rs2238135 |
| PheGenI | rs2238135 |
| Biobank | rs2238135 |
| 1000 genomes | rs2238135 |
| hgdp | rs2238135 |
| ensembl | rs2238135 |
| geneview | rs2238135 |
| scholar | rs2238135 |
| rs2238135 | |
| pharmgkb | rs2238135 |
| gwascentral | rs2238135 |
| openSNP | rs2238135 |
| 23andMe | rs2238135 |
| SNPshot | rs2238135 |
| SNPdbe | rs2238135 |
| MSV3d | rs2238135 |
| GWAS Ctlg | rs2238135 |
| GMAF | 0.2456 |
| Max Magnitude | 0 |
rs2238135 is a SNP in the vitamin D VDR receptor gene.
rs2238135(G;G) homozygotes were associated with an ~2.5x higher risk of prostate cancer compared to homozygote carriers of the more common (C) allele in the 630 Caucasian patients studied.[PMID 17932346]
[PMID 17130574] Protection from type 1 diabetes by vitamin D receptor haplotypes.
[PMID 19255064
] Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.
[PMID 19454612] Vitamin D pathway gene variants and prostate cancer risk.
[PMID 19753122] Analysis of SNPs and haplotypes in vitamin D pathway genes and renal cancer risk.
[PMID 23189278] VDR gene single nucleotide polymorphisms and their association with risk of oral cavity carcinoma
