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rs2279381

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;G) 2 Sleep might be more fragmented (no particular negative consequences)
(G;G) 0 common/normal


Make rs2279381(A;A)
ReferenceGRCh38.p7 38.3/150
Chromosome6
Position122780399
GeneFABP7
is asnp
is mentioned by
dbSNPrs2279381
dbSNP (old)rs2279381
ClinGenrs2279381
ebirs2279381
HLIrs2279381
Exacrs2279381
Gnomadrs2279381
Varsomers2279381
Maprs2279381
PheGenIrs2279381
Biobankrs2279381
1000 genomesrs2279381
hgdprs2279381
ensemblrs2279381
gopubmedrs2279381
geneviewrs2279381
scholarrs2279381
googlers2279381
pharmgkbrs2279381
gwascentralrs2279381
openSNPrs2279381
23andMers2279381
23andMe allrs2279381
SNPshotrs2279381
SNPdbers2279381
MSV3drs2279381
GWAS Ctlgrs2279381
Max Magnitude2
? (A;A) (A;G) (G;G) 28

rs2279381, also known as c.502C>T, p.Thr61Met and T61M, represents a variant in the FABP7 gene on chromosome 6.

A 2017 study of ~300 Japanese adult males monitored for a week found that the 10% carrying a variant rs2279381(A) allele exhibited more fragmented sleep than non-carriers. Specifically, although total amount of sleep was the same, carriers had sleep cycle bouts averaging 14 minutes compared to 18 minutes for non-carriers, and 27 bouts of sleep/wake vs 24 for non-carriers. No particular negative consequences were associated with the difference in sleep fragmentation.[PMID 28435883OA-icon.png]