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rs234706(A;G)

From SNPedia
0.94 reduced risk of cleft lip / palate
Is agenotype
ofrs234706
GeneCBS, CBSL
Chromosome21
Position43,065,240
mentionedby
Magnitude1.1
ReputeGood
Geno Mag Summary
(A;A) 2.5 0.50 reduced risk of cleft lip / palate, 0.51 reduced risk of non-Hodgkin lymphoma. Increased responsiveness to homocysteine-lowering effects of folic acid.
(A;G) 1.1 0.94 reduced risk of cleft lip / palate
(G;G) 0 common in clinvar

We found a reduced risk of CL/P with mothers who carried the CBS C699T variant (rs234706); relative risk was 0.94 with one copy of the T allele (95% CI 0.63-1.4) and 0.50 (95% CI 0.26-0.96) with two copies (P = 0.008).

PMID: 18203168