Have questions? Visit https://www.reddit.com/r/SNPedia

rs2395185(G;G)

From SNPedia
1.33x increased risk of Ulcerative Colitis, but much lower Type 1 Diabetes risk.
Is agenotype
ofrs2395185
Gene
Chromosome6
Position32,465,390
mentionedby
Magnitude2
ReputeGood
Geno Mag Summary
(G;G) 2 1.33x increased risk of Ulcerative Colitis, but much lower Type 1 Diabetes risk.
(G;T) 2 2.72x higher risk of Type 1 Diabetes, but 0.88x lower risk of Ulcerative Colitis.
(T;T) 3 9.49x risk of Type 1 Diabetes, but 0.58x lower risk of Ulcerative Colitis.

This raises the risk of Ulcerative Colitis (according to 23andMe), but also greatly lowers the risk of Type 1 Diabetes.[PMID 19837788] It may also affect other autoimmune diseases.