rs281865054

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(G;G)	0	common in clinvar
(G;T)	6.5	Parkinson's disease mutation, adult-onset

Make rs281865054(T;T)

Reference

GRCh38 38.1/141

Chromosome

12

Position

40323270

Gene

LRRK2

is a	snp
is	mentioned by
dbSNP	rs281865054
dbSNP (classic)	rs281865054
ClinGen	rs281865054
ebi	rs281865054
HLI	rs281865054
Exac	rs281865054
Gnomad	rs281865054
Varsome	rs281865054
LitVar	rs281865054
Map	rs281865054
PheGenI	rs281865054
Biobank	rs281865054
1000 genomes	rs281865054
hgdp	rs281865054
ensembl	rs281865054
geneview	rs281865054
scholar	rs281865054
google	rs281865054
pharmgkb	rs281865054
gwascentral	rs281865054
openSNP	rs281865054
23andMe	rs281865054
SNPshot	rs281865054
SNPdbe	rs281865054
MSV3d	rs281865054
GWAS Ctlg	rs281865054

Max Magnitude

6.5

c.5620G>T (p.Glu1874Ter)

23andMe calls this i5045553

ClinVar
Risk	rs281865054(A;A) rs281865054(T;T)
Alt	rs281865054(A;A) rs281865054(T;T)
Reference	Rs281865054(G;G)
Significance	Pathogenic
Disease	Parkinson disease 8
Variation	info
Gene	LRRK2
CLNDBN	Parkinson disease 8, autosomal dominant
Reversed	0
HGVS	NC_000012.11:g.40717072G>T
CLNSRC	ClinVar GeneReviews
CLNACC	RCV000032489.1,

[PMID 16633828] A common missense variant in the LRRK2 gene, Gly2385Arg, associated with Parkinson's disease risk in Taiwan.