rs2853498(G;G)
From SNPedia
| 12308+, MT-Haplogroup U or K. |
| Is a | genotype |
| of | rs2853498 |
| Gene | |
| Chromosome | MT |
| Position | 12,308 |
| mentioned | by |
| Magnitude | 1.5 |
| Repute | Bad |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0.1 | 12308-, not MT-Haplogroup U or K. |
| (G;G) | 1.5 | 12308+, MT-Haplogroup U or K. |
One of the three SNPs required for Mitochondrial haplogroup U or K is present. This also indicates a mutation in the mitochondrial gene for building proteins containing the amino acid Leucine. It has been linked to a 1.5x increased risk of Age-related Macular Degeneration.
