rs28934874

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(A;C)	7	Li-Fraumeni Syndrome (predicted)
(C;C)	0	common in clinvar

Make rs28934874(A;A)

Reference

GRCh38 38.1/141

Chromosome

17

Position

7675161

Gene

TP53

is a	snp
is	mentioned by
dbSNP	rs28934874
dbSNP (classic)	rs28934874
ClinGen	rs28934874
ebi	rs28934874
HLI	rs28934874
Exac	rs28934874
Gnomad	rs28934874
Varsome	rs28934874
LitVar	rs28934874
Map	rs28934874
PheGenI	rs28934874
Biobank	rs28934874
1000 genomes	rs28934874
hgdp	rs28934874
ensembl	rs28934874
geneview	rs28934874
scholar	rs28934874
google	rs28934874
pharmgkb	rs28934874
gwascentral	rs28934874
openSNP	rs28934874
23andMe	rs28934874
SNPshot	rs28934874
SNPdbe	rs28934874
MSV3d	rs28934874
GWAS Ctlg	rs28934874

Max Magnitude

7

OMIM	191170
Desc	BREAST CANCER
Variant	0025
Related	also

OMIM	191170
Desc
Variant	0026
Related	also

ClinVar
Risk	rs28934874(A;A) rs28934874(G;G) rs28934874(T;T)
Alt	rs28934874(A;A) rs28934874(G;G) rs28934874(T;T)
Reference	Rs28934874(C;C)
Significance	Pathogenic
Disease	Breast adenocarcinoma not provided Hereditary cancer-predisposing syndrome Malignant melanoma of skin Adenocarcinoma of stomach Oesophageal carcinoma Malignant neoplasm of body of uterus Ovarian Serous Cystadenocarcinoma Multiple myeloma Adenocarcinoma of lung Colorectal Neoplasms Uterine Carcinosarcoma Adenoid cystic carcinoma Squamous cell carcinoma of the head and neck Neoplasm of brain Squamous cell carcinoma of lung Neoplasm of breast Pancreatic adenocarcinoma Hepatocellular carcinoma Transitional cell carcinoma of the bladder Li-Fraumeni syndrome
Variation	info
Gene	TP53
CLNDBN	Breast adenocarcinoma not provided Hereditary cancer-predisposing syndrome Malignant melanoma of skin Adenocarcinoma of stomach Oesophageal carcinoma Malignant neoplasm of body of uterus Ovarian Serous Cystadenocarcinoma Multiple myeloma Adenocarcinoma of lung Colorectal Neoplasms Uterine Carcinosarcoma Adenoid cystic carcinoma Squamous cell carcinoma of the head and neck Neoplasm of brain Squamous cell carcinoma of lung Neoplasm of breast Pancreatic adenocarcinoma Hepatocellular carcinoma Transitional cell carcinoma of the bladder Li-Fraumeni syndrome
Reversed	1
HGVS	NC_000017.10:g.7578479G>A; NC_000017.10:g.7578479G>C; NC_000017.10:g.7578479G>T
CLNSRC	HGMD OMIM Allelic Variant UniProtKB (protein)
CLNACC	RCV000013169.6, RCV000079203.4, RCV000219702.1, RCV000420199.1, RCV000420869.1, RCV000421928.1, RCV000422996.1, RCV000424996.1, RCV000426058.1, RCV000427411.1, RCV000429847.1, RCV000431507.1, RCV000432585.1, RCV000433689.1, RCV000435681.1, RCV000438074.1, RCV000440140.1, RCV000440887.1, RCV000443020.1, RCV000443379.1, RCV000418125.1, RCV000419693.1, RCV000420838.1, RCV000420971.1, RCV000425371.1, RCV000426064.1, RCV000426471.1, RCV000428371.1, RCV000431059.1, RCV000431789.1, RCV000432886.1, RCV000436762.1, RCV000437396.1, RCV000438632.1, RCV000441351.1, RCV000443299.1, RCV000443386.1, RCV000459465.1, RCV000013168.4, RCV000130617.3, RCV000417493.1, RCV000418145.1, RCV000422094.1, RCV000423161.1, RCV000424222.1, RCV000425139.1, RCV000428384.1, RCV000428836.1, RCV000429500.1, RCV000433405.1, RCV000434485.1, RCV000435159.1, RCV000437544.1, RCV000439740.1, RCV000440812.1, RCV000442802.1, RCV000443817.1,