rs80357545

minus

Geno	Mag	Summary
(-;T)	6	BRCA1 variant considered pathogenic for breast cancer
(T;T)	0	common in clinvar

Make rs80357545(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43091749

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357545
dbSNP (classic)	rs80357545
ClinGen	rs80357545
ebi	rs80357545
HLI	rs80357545
Exac	rs80357545
Gnomad	rs80357545
Varsome	rs80357545
LitVar	rs80357545
Map	rs80357545
PheGenI	rs80357545
Biobank	rs80357545
1000 genomes	rs80357545
hgdp	rs80357545
ensembl	rs80357545
geneview	rs80357545
scholar	rs80357545
google	rs80357545
pharmgkb	rs80357545
gwascentral	rs80357545
openSNP	rs80357545
23andMe	rs80357545
SNPshot	rs80357545
SNPdbe	rs80357545
MSV3d	rs80357545
GWAS Ctlg	rs80357545

Max Magnitude

6

rs80357545, also known as 3901delT, c.3782_3782delT and p.Leu1261Tyrfs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80357545(-;-)
Alt	rs80357545(-;-)
Reference	Rs80357545(T;T)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA1
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 1
Reversed	1
HGVS	NC_000017.10:g.41243766delA
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000048331.2, RCV000112184.3,