rs9273363
23andMe's Type 1 Diabetes SNP |
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(A;A) | 2 | Higher risk of Type 1 Diabetes. |
(A;C) | 2 | Lower 0.87x risk of Type 1 Diabetes. |
(C;C) | 2.1 | Much lower 0.15x risk of Type 1 Diabetes. |
Reference | GRCh38 38.1/141 |
Chromosome | 6 |
Position | 32658495 |
Gene | HLA-DQB1-AS1 |
is a | snp |
is | mentioned by |
dbSNP | rs9273363 |
dbSNP (classic) | rs9273363 |
ClinGen | rs9273363 |
ebi | rs9273363 |
HLI | rs9273363 |
Exac | rs9273363 |
Gnomad | rs9273363 |
Varsome | rs9273363 |
LitVar | rs9273363 |
Map | rs9273363 |
PheGenI | rs9273363 |
Biobank | rs9273363 |
1000 genomes | rs9273363 |
hgdp | rs9273363 |
ensembl | rs9273363 |
geneview | rs9273363 |
scholar | rs9273363 |
rs9273363 | |
pharmgkb | rs9273363 |
gwascentral | rs9273363 |
openSNP | rs9273363 |
23andMe | rs9273363 |
SNPshot | rs9273363 |
SNPdbe | rs9273363 |
MSV3d | rs9273363 |
GWAS Ctlg | rs9273363 |
GMAF | 0.2576 |
Max Magnitude | 2.1 |
? | (A;A) (A;C) (C;C) | 28 |
---|---|---|
|
This is one of the SNPs that 23andMe uses for Type 1 diabetes. According to 23andMe, this SNP changes your risk of Type 1 Diabetes. That is an autoimmune disease where your immune system attacks your own body's insulin producing cells in the pancreas, preventing your blood sugar from being able to enter cells that need energy. This has been verified for white people. 23andMe originally wanted to use rs9272346 instead, but it was deemed unreliable.
GWAS snp | |
---|---|
PMID | [PMID 23770605] |
Trait | Chronic lymphocytic leukemia |
Title | Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. |
Risk Allele | A |
P-val | 2E-10 |
Odds Ratio | 1.24 [NR] |
[PMID 19956648] Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases.
[PMID 20018019] Two-stage joint selection method to identify candidate markers from genome-wide association studies.