Have questions? Visit https://www.reddit.com/r/SNPedia

rs9340799(A;A)

From SNPedia
Women have lower risk of Endometriosis but normal risk for Endometrial Cancer, and more cognitive impairment with age.
Is agenotype
ofrs9340799
GeneESR1
Chromosome6
Position151,842,246
mentionedby
Magnitude2
ReputeGood
Geno Mag Summary
(A;A) 2 Women have lower risk of Endometriosis but normal risk for Endometrial Cancer, and more cognitive impairment with age.
(A;G) 2 Women have normal (lower) risk of Endometriosis, 0.75x lower risk of Endometrial Cancer, and normal (higher) risk of cognitive impairment.
(G;G) 3 Women have 10x risk of Endometriosis, but half the risk of Endometrial Cancer and 0.76x less cognitive impairment.

Men have zero risk, but can pass this on to their daughters. This is the normal version of Estrogen Receptor 1 (alpha). It has more cognitive decline than the rare version, with old women only remembering half as much details on the East Boston Memory Test immediate recall test.