DRD2

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is agene
is mentioned by
Full namedopamine receptor D2
EntrezGene1813
PheGenI1813
VariationViewer1813
ClinVarDRD2
dbSNP1813
SADR1813
HugeNav1813
wikipediaDRD2
googleDRD2
gopubmedDRD2
EVSDRD2
HEFalMpDRD2
23andMeDRD2
UniProtP14416
EnsemblENSG00000149295
OMIM126450
EVSDRD2
# SNPs33
 Max MagnitudeChromosome positionSummary
Rs104894220113,416,935
Rs1076560113,412,966
Rs1076562113,425,286
Rs1079596113,425,897
Rs1079597113,425,564
Rs1079598113,425,552
Rs1079727113,418,460
Rs11214606113,439,147
Rs11214613113,464,537
Rs1124493113,411,573
Rs1125394113,426,463
Rs12363125113,415,194
Rs12364283113,476,233
Rs1554929113,408,042
Rs1799732113,475,529
Rs1799978113,475,629
Rs1800496113,412,766
Rs1800498113,420,866
Rs1801028113,412,762
Rs2234689113,407,761
Rs2242592113,408,708
Rs2283265113,414,814
Rs2734839113,415,768
Rs2734841113,411,054
Rs2734842113,409,552
Rs4436578113,436,043
Rs4648317113,460,810
Rs4648319113,443,641
Rs4938019113,470,669
Rs6275113,412,755
Rs6276113,410,675
Rs6277113,412,737
Rs6279113,410,351

DRD2 encodes the Dopamine receptor D2, a target of various psychotropic agents, connected to memory and behavior.

SNPs in include:

[PMID 18063800] Genetically determined differences in learning from errors.

[1] Compared with DRD2 A1 carriers, subjects homozygous for the DRD2 A2 allele performed poorer in a measure of general cognitive functioning (MMSE) and in long term verbal memory. Our findings suggest that among the aged with cognitive impairments, the homozygous status for the A2 allele of the DRD2 Taq I polymorphism is associated with diminished cognitive performance and increased atrophy in the striatum.