rs1052576(A;A)
From SNPedia
| 0.5x reduced risk of multiple myeloma, general reduced risk of cancer |
| Is a | genotype |
| of | rs1052576 |
| Gene | CASP9 |
| Chromosome | 1 |
| Position | 15,506,048 |
| mentioned | by |
| Magnitude | 1.7 |
| Repute | Good |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 1.7 | 0.5x reduced risk of multiple myeloma, general reduced risk of cancer |
| (A;G) | 1.5 | 0.8x reduced risk of multiple myeloma, general reduced risk of cancer |
| (G;G) | 1 | Increased risk of multiple myeloma, B-cell neoplasms, and cancer in general |
A number of small studies with fairly low p-values, but with low heterogeneity across studies, show a protective effect for the A allele which is greater in homozygotes.
