rs11978267
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(A;A) | 0 | normal/common |
(G;G) | 2 | possible increased risk for infant acute myeloid leukemia (AML) |
Make rs11978267(A;G) |
Reference | GRCh38 38.1/141 |
Chromosome | 7 |
Position | 50398606 |
Gene | IKZF1 |
is a | snp |
is | mentioned by |
dbSNP | rs11978267 |
dbSNP (classic) | rs11978267 |
ClinGen | rs11978267 |
ebi | rs11978267 |
HLI | rs11978267 |
Exac | rs11978267 |
Gnomad | rs11978267 |
Varsome | rs11978267 |
LitVar | rs11978267 |
Map | rs11978267 |
PheGenI | rs11978267 |
Biobank | rs11978267 |
1000 genomes | rs11978267 |
hgdp | rs11978267 |
ensembl | rs11978267 |
geneview | rs11978267 |
scholar | rs11978267 |
rs11978267 | |
pharmgkb | rs11978267 |
gwascentral | rs11978267 |
openSNP | rs11978267 |
23andMe | rs11978267 |
SNPshot | rs11978267 |
SNPdbe | rs11978267 |
MSV3d | rs11978267 |
GWAS Ctlg | rs11978267 |
GMAF | 0.2282 |
Max Magnitude | 2 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
GWAS snp | |
---|---|
PMID | [PMID 19684603] |
Trait | Acute lymphoblastic leukemia (childhood) |
Title | Germline genomic variants associated with childhood acute lymphoblastic leukemia |
Risk Allele | G |
P-val | 8E-11 |
Odds Ratio | 1.69 [1.40-1.90] |
[PMID 22422485] Genetic variants modify susceptibility to leukemia in infants: A Children's Oncology Group report
[PMID 23692655] ARID5B and IKZF1 variants, selected demographic factors, and childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group
[PMID 24564228] ARID5B polymorphism confers an increased risk to acquire specific MLL rearrangements in early childhood leukemia
[PMID 28768142] Contributions of IKZF1, DDC, CDKN2A, CEBPE, and LMO1 Gene Polymorphisms to Acute Lymphoblastic Leukemia in a Yemeni Population.
[PMID 31604453] IKZF1 genetic variants rs4132601 and rs11978267 and acute lymphoblastic leukemia risk in Tunisian children: a case-control study.