rs11978267(G;G)
From SNPedia
possible increased risk for infant acute myeloid leukemia (AML) |
Is a | genotype |
of | rs11978267 |
Gene | IKZF1 |
Chromosome | 7 |
Position | 50,398,606 |
mentioned | by |
Magnitude | 2 |
Repute | Bad |
Geno | Mag | Summary |
---|---|---|
(A;A) | 0 | normal/common |
(G;G) | 2 | possible increased risk for infant acute myeloid leukemia (AML) |
Although based on a fairly small study (~170 pediatric patients), homozygosity for this relatively rare IKZF1 gene allele has been reported to increase risk (perhaps 3+ fold) of infant acute myeloid leukemia (AML).