rs16023
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in clinvar |
| Make rs16023(A;T) |
| Make rs16023(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 19 |
| Position | 13298658 |
| Gene | CACNA1A |
| is a | snp |
| is | mentioned by |
| dbSNP | rs16023 |
| dbSNP (classic) | rs16023 |
| ClinGen | rs16023 |
| ebi | rs16023 |
| HLI | rs16023 |
| Exac | rs16023 |
| Gnomad | rs16023 |
| Varsome | rs16023 |
| LitVar | rs16023 |
| Map | rs16023 |
| PheGenI | rs16023 |
| Biobank | rs16023 |
| 1000 genomes | rs16023 |
| hgdp | rs16023 |
| ensembl | rs16023 |
| geneview | rs16023 |
| scholar | rs16023 |
| rs16023 | |
| pharmgkb | rs16023 |
| gwascentral | rs16023 |
| openSNP | rs16023 |
| 23andMe | rs16023 |
| SNPshot | rs16023 |
| SNPdbe | rs16023 |
| MSV3d | rs16023 |
| GWAS Ctlg | rs16023 |
| GMAF | 0.1244 |
| Max Magnitude | 0 |
rs16023, also known as E993V, is a SNP in the calcium channel, voltage-dependent, P/Q type, alpha 1A subunit CACNA1A gene.
On it's own it is not associated with migraines; however, individuals with both this SNP and a variant rs16022 have a 2x increased risk of any type of migraine, at least if a study of ~100 Italian patients is correct.[PMID 19429006]
| ClinVar | |
|---|---|
| Risk | rs16023(T;T) |
| Alt | rs16023(T;T) |
| Reference | Rs16023(A;A) |
| Significance | Other |
| Disease | not provided not specified |
| Variation | info |
| Gene | CACNA1A |
| CLNDBN | not provided not specified |
| Reversed | 1 |
| HGVS | NC_000019.9:g.13409472T>A |
| CLNSRC | HGMD UniProtKB (variants) |
| CLNACC | RCV000059297.1, RCV000116521.7, |
[PMID 16866717] Migrainous vertigo: mutation analysis of the candidate genes CACNA1A, ATP1A2, SCN1A, and CACNB4.
