rs17036170(A;G)
From SNPedia
Increased risk of drug induced liver injury with diclofenac |
Is a | genotype |
of | rs17036170 |
Gene | PPARG |
Chromosome | 3 |
Position | 12,288,912 |
mentioned | by |
Magnitude | 1.9 |
Repute | Bad |
Geno | Mag | Summary |
---|---|---|
(A;A) | 2 | Elevated risk for drug induced liver injury with diclofenac |
(A;G) | 1.9 | Increased risk of drug induced liver injury with diclofenac |
(G;G) | 0 | common/normal |
This uncommon risk allele A was found in a GWAS to be associated with drug induced liver injury with diclofenac. OR = 11.3 (4.9–25.9) Replicability is uncertain, but individuals with this genotype should be aware of the potential of increased risk.