rs2395029(G;T)
From SNPedia
HLA-B*5701 carrier most likely (if Caucasian or Hispanic) |
Is a | genotype |
of | rs2395029 |
Gene | HCP5 |
Chromosome | 6 |
Position | 31,464,003 |
mentioned | by |
Magnitude | 3.2 |
Repute | Bad |
Geno | Mag | Summary |
---|---|---|
(G;G) | 4 | HLA-B*5701 homozygote likely if Caucasian or Hispanic; high risk for hypersensitivity to various drugs including abacavir; 2x psoriasis risk; see details |
(G;T) | 3.2 | HLA-B*5701 carrier most likely (if Caucasian or Hispanic) |
(T;T) | 0 | common |
risk for hypersensitivity to various drugs including abacavir
This genotype is associated with an HIV viral load 1 log (10 fold) lower than the most common genotype (rs2395029(T;T)). [PMID 17641165]
Possible 2x higher risk for psoriasis
The (G) allele frequency is only 0.05 which means only about 1 in 10 people have this genotype.