Cancer

Accounting for ~22% of all deaths, cancer is the second leading cause of death in most developed countries, behind only heart disease. General information can be found in the Wikipedia article.

50% of men and 33% of women will be diagnosed with cancer. A "healthy lifestyle pattern" significantly reduces overall risk for cancer [PMID 27196525].

5-10% of cancers are considered hereditary in origin, MD Anderson youtube video

See also

• Bladder cancer
• Breast cancer
• Colon cancer
• Endometrial cancer
• Gastric cancer
• Head and neck cancer
• Lung cancer
• Lymphoma
• Ovarian cancer
• Pancreatic cancer
• Prostate cancer
• Skin cancer
• Testicular cancer
• Wilms tumor

A SNP that reduces cancer risk among Chinese

Variations in the p53 tumor supressor protein affect cancer susceptibility.

A synthetic molecule causes cancer cells to self-destruct by activating an enzyme called procapsase-3.

rs2273535 is reported to play a role in several cancers [PMID 15802297]

A variant was found in the SUOX gene in a "cancer cluster" of children with leukemia; the variant also appeared in about 40 percent of children in a control group.

A SNP in the DNA repair gene RAD1 lowers the risk of squamous cell carcinoma of the head and neck. [PMID 17118968]

esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma [PMID 16536979]