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rs10903129

From SNPedia

Orientationplus
Stabilizedplus
Make rs10903129(A;A)
Make rs10903129(A;G)
Make rs10903129(G;G)
ReferenceGRCh38 38.1/141
Chromosome1
Position25442446
GeneTMEM57
is asnp
is mentioned by
dbSNPrs10903129
ebirs10903129
HLIrs10903129
Exacrs10903129
Varsomers10903129
Maprs10903129
PheGenIrs10903129
hapmaprs10903129
1000 genomesrs10903129
hgdprs10903129
ensemblrs10903129
gopubmedrs10903129
geneviewrs10903129
scholarrs10903129
googlers10903129
pharmgkbrs10903129
gwascentralrs10903129
openSNPrs10903129
23andMers10903129
23andMe allrs10903129
SNP Nexus

SNPshotrs10903129
SNPdbers10903129
MSV3drs10903129
GWAS Ctlgrs10903129
GMAF0.4959
Max Magnitude
? (A;A) (A;G) (G;G) 28
per the 23andMe blog, the minor allele of this SNP (A) was associated with decreased cholesterol and triglycerides
SNP Rarer allele LDL HDL TG
rs6544713 T +
rs2650000 A +
rs471364 C -
rs1800961 T -
rs7679 C - +
rs2967605 T -
rs2409722 T -
rs10903129 A - - -
rs6756629 A - + -
rs12670798 C + + +
rs7395662 A - + +
rs174570 T - - +
rs2271293 A - + -
rs2624265 C +
rs2167079 T +
rs9891572 T +
rs4844614 T +
rs5031002 G +
GWAS snp
PMID [PMID 19060911OA-icon.png]
Trait Cholesterol, total
Title Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
Risk Allele G
P-val 5E-10
Odds Ratio 0.06 [NR] SD increase


GWAS snp
PMID [PMID 21700265OA-icon.png]
Trait
Title Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate.
Risk Allele
P-val 5E-13
Odds Ratio 0.1000 [NR] unit decrease


[PMID 20084173OA-icon.png] Magnitude of stratification in human populations and impacts on genome wide association studies.


[PMID 21304891OA-icon.png] A study of CNVs as trait-associated polymorphisms and as expression quantitative trait loci.


GET Evidence
rs10903129
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.59375
summary



[PMID 23856853OA-icon.png] Association of a complement receptor 1 gene variant with baseline erythrocyte sedimentation rate levels in patients starting anti-TNF therapy in a UK rheumatoid arthritis cohort: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort.