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rs6544713

From SNPedia

Orientationplus
Stabilizedplus
Make rs6544713(C;C)
Make rs6544713(C;T)
Make rs6544713(T;T)
ReferenceGRCh38 38.1/141
Chromosome2
Position43846742
GeneABCG8
is asnp
is mentioned by
dbSNPrs6544713
ebirs6544713
HLIrs6544713
Exacrs6544713
Varsomers6544713
Maprs6544713
PheGenIrs6544713
hapmaprs6544713
1000 genomesrs6544713
hgdprs6544713
ensemblrs6544713
gopubmedrs6544713
geneviewrs6544713
scholarrs6544713
googlers6544713
pharmgkbrs6544713
gwascentralrs6544713
openSNPrs6544713
23andMers6544713
23andMe allrs6544713
SNP Nexus

SNPshotrs6544713
SNPdbers6544713
MSV3drs6544713
GWAS Ctlgrs6544713
GMAF0.1736
Max Magnitude
? (C;C) (C;T) (T;T) 28
[PMID 23202125OA-icon.png] Large-scale association analysis identifies new risk loci for coronary artery disease.

}}per the 23andMe blog, the minor allele of this SNP (T) was associated with increased LDL cholesterol

SNP Rarer allele LDL HDL TG
rs6544713 T +
rs2650000 A +
rs471364 C -
rs1800961 T -
rs7679 C - +
rs2967605 T -
rs2409722 T -
rs10903129 A - - -
rs6756629 A - + -
rs12670798 C + + +
rs7395662 A - + +
rs174570 T - - +
rs2271293 A - + -
rs2624265 C +
rs2167079 T +
rs9891572 T +
rs4844614 T +
rs5031002 G +
GWAS snp
PMID [PMID 19060906OA-icon.png]
Trait LDL cholesterol
Title Common variants at 30 loci contribute to polygenic dyslipidemia
Risk Allele T
P-val 2E-20
Odds Ratio 0.15 [0.11-0.19] SD increase


[PMID 23202125OA-icon.png] Large-scale association analysis identifies new risk loci for coronary artery disease. [PMID 19951432OA-icon.png] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.

[PMID 19913121OA-icon.png] Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.


GET Evidence
rs6544713
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.765625
summary