Have questions? Visit https://www.reddit.com/r/SNPedia

rs12670798

From SNPedia

Orientationplus
Stabilizedplus
Make rs12670798(C;C)
Make rs12670798(C;T)
Make rs12670798(T;T)
ReferenceGRCh38 38.1/141
Chromosome7
Position21567734
GeneDNAH11
is asnp
is mentioned by
dbSNPrs12670798
ebirs12670798
HLIrs12670798
Exacrs12670798
Varsomers12670798
Maprs12670798
PheGenIrs12670798
hapmaprs12670798
1000 genomesrs12670798
hgdprs12670798
ensemblrs12670798
gopubmedrs12670798
geneviewrs12670798
scholarrs12670798
googlers12670798
pharmgkbrs12670798
gwascentralrs12670798
openSNPrs12670798
23andMers12670798
23andMe allrs12670798
SNP Nexus

SNPshotrs12670798
SNPdbers12670798
MSV3drs12670798
GWAS Ctlgrs12670798
GMAF0.3081
Max Magnitude
? (C;C) (C;T) (T;T) 28
per the 23andMe blog, the minor allele of this SNP (C) was associated with increased cholesterol and triglycerides
SNP Rarer allele LDL HDL TG
rs6544713 T +
rs2650000 A +
rs471364 C -
rs1800961 T -
rs7679 C - +
rs2967605 T -
rs2409722 T -
rs10903129 A - - -
rs6756629 A - + -
rs12670798 C + + +
rs7395662 A - + +
rs174570 T - - +
rs2271293 A - + -
rs2624265 C +
rs2167079 T +
rs9891572 T +
rs4844614 T +
rs5031002 G +
GWAS snp
PMID [PMID 19060911OA-icon.png]
Trait Cholesterol, total
Title Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
Risk Allele G
P-val 9E-7
Odds Ratio 0.06 [NR] SD increase



GWAS snp
PMID [PMID 20686565OA-icon.png]
Trait
Title Biological, clinical and population relevance of 95 loci for blood lipids.
Risk Allele T
P-val 7E-10
Odds Ratio 1.7000 None


[PMID 19951432OA-icon.png] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.


[PMID 20502693OA-icon.png] Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.


GET Evidence
rs12670798
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.273438
summary



GWAS snp
PMID [PMID 24097068OA-icon.png]
Trait Cholesterol, total
Title Discovery and refinement of loci associated with lipid levels.
Risk Allele C
P-val 1E-16
Odds Ratio .04 [NR] unit increase