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rs2650000

From SNPedia

Orientationminus
Stabilizedminus
Make rs2650000(G;G)
Make rs2650000(G;T)
Make rs2650000(T;T)
ReferenceGRCh38 38.1/141
Chromosome12
Position120951159
is asnp
is mentioned by
dbSNPrs2650000
ebirs2650000
HLIrs2650000
Exacrs2650000
Varsomers2650000
Maprs2650000
PheGenIrs2650000
hapmaprs2650000
1000 genomesrs2650000
hgdprs2650000
ensemblrs2650000
gopubmedrs2650000
geneviewrs2650000
scholarrs2650000
googlers2650000
pharmgkbrs2650000
gwascentralrs2650000
openSNPrs2650000
23andMers2650000
23andMe allrs2650000
SNP Nexus

SNPshotrs2650000
SNPdbers2650000
MSV3drs2650000
GWAS Ctlgrs2650000
GMAF0.3274
Max Magnitude
? (G;G) (G;T) (T;T) 28
per the 23andMe blog, the minor allele of this SNP (A) was associated with increased LDL cholesterol
SNP Rarer allele LDL HDL TG
rs6544713 T +
rs2650000 A +
rs471364 C -
rs1800961 T -
rs7679 C - +
rs2967605 T -
rs2409722 T -
rs10903129 A - - -
rs6756629 A - + -
rs12670798 C + + +
rs7395662 A - + +
rs174570 T - - +
rs2271293 A - + -
rs2624265 C +
rs2167079 T +
rs9891572 T +
rs4844614 T +
rs5031002 G +
GWAS snp
PMID [PMID 19060906OA-icon.png]
Trait LDL cholesterol
Title Common variants at 30 loci contribute to polygenic dyslipidemia
Risk Allele A
P-val 2E-8
Odds Ratio 0.07 [0.03-0.11] SD increase
GWAS snp
PMID [PMID 19060910OA-icon.png]
Trait Other metabolic traits
Title Genome-wide association analysis of metabolic traits in a birth cohort from a founder population
Risk Allele A
P-val 3E-11
Odds Ratio 0.40 [0.25-0.55] mmol/l decrease




[PMID 18439548OA-icon.png] Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.


[PMID 19474294OA-icon.png] Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.


[PMID 19951432OA-icon.png] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.


GET Evidence
rs2650000
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.78125
summary