rs174570
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(C;C) | 0 |
Make rs174570(C;T) |
Make rs174570(T;T) |
Reference | GRCh38 38.1/141 |
Chromosome | 11 |
Position | 61829740 |
Gene | FADS2 |
is a | snp |
is | mentioned by |
dbSNP | rs174570 |
dbSNP (classic) | rs174570 |
ClinGen | rs174570 |
ebi | rs174570 |
HLI | rs174570 |
Exac | rs174570 |
Gnomad | rs174570 |
Varsome | rs174570 |
LitVar | rs174570 |
Map | rs174570 |
PheGenI | rs174570 |
Biobank | rs174570 |
1000 genomes | rs174570 |
hgdp | rs174570 |
ensembl | rs174570 |
geneview | rs174570 |
scholar | rs174570 |
rs174570 | |
pharmgkb | rs174570 |
gwascentral | rs174570 |
openSNP | rs174570 |
23andMe | rs174570 |
SNPshot | rs174570 |
SNPdbe | rs174570 |
MSV3d | rs174570 |
GWAS Ctlg | rs174570 |
GMAF | 0.2351 |
Max Magnitude | 0 |
? | (C;C) (C;T) (T;T) | 28 |
---|---|---|
|
per the 23andMe blog, the minor allele of this SNP (T) was associated with decreased cholesterol and increased triglycerides
SNP | Rarer allele | LDL | HDL | TG |
---|---|---|---|---|
rs6544713 | T | + | ||
rs2650000 | A | + | ||
rs471364 | C | - | ||
rs1800961 | T | - | ||
rs7679 | C | - | + | |
rs2967605 | T | - | ||
rs2409722 | T | - | ||
rs10903129 | A | - | - | - |
rs6756629 | A | - | + | - |
rs12670798 | C | + | + | + |
rs7395662 | A | - | + | + |
rs174570 | T | - | - | + |
rs2271293 | A | - | + | - |
rs2624265 | C | + | ||
rs2167079 | T | + | ||
rs9891572 | T | + | ||
rs4844614 | T | + | ||
rs5031002 | G | + |
GWAS snp | |
---|---|
PMID | [PMID 19060911] |
Trait | Cholesterol, total |
Title | Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts |
Risk Allele | G |
P-val | 2E-10 |
Odds Ratio | 0.09 [NR] SD increase |
[PMID 20484448] Dietary n-3 and n-6 polyunsaturated fatty acid intake interacts with FADS1 genetic variation to affect total and HDL-cholesterol concentrations in the Doetinchem Cohort Study
[PMID 19798445] Genetic determinants of circulating sphingolipid concentrations in European populations.
[PMID 19944404] Genomic dissection of population substructure of Han Chinese and its implication in association studies.
[PMID 19951432] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.
[PMID 20502693] Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.
[PMID 20565855] Genetic variation in lipid desaturases and its impact on the development of human disease.
[PMID 21383846] Genetic variants of the FADS gene cluster and ELOVL gene family, colostrums LC-PUFA levels, breastfeeding, and child cognition.
rs7115739 and rs174570 http://www.sciencemag.org/content/349/6254/1343.full Greenlandic Inuit show genetic signatures of diet and climate adaptation
GWAS snp | |
---|---|
PMID | [PMID 24647736] |
Trait | Glycated hemoglobin levels |
Title | Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians. |
Risk Allele | C |
P-val | 2E-7 |
Odds Ratio | .04 [0.020-0.060] unit increase |